Department of Pharmacology

Research

Research information is being updated.

Publications

• Emodin, a potent anthraquinone mitigates MPTP-induced parkinsons’ disease pathology by regulating Nrf2 and its downstream targets: in Silico and in vivo approach — Sarwat Jahan, Muhammad Ikram, Sami Siraj, Shakir Ullah, Muhammad Zakria, Nasir Ahmad , Journal (2025) — Dr. Nasir Ahmad
• Impact of ABCB1 gene polymorphism on clopidogrel plasma concentration and cardiovascular events in post-PCI patients — Abdur Razaq, Waheed Iqbal, Syed Tahir Shah, Muhammad Abdur Rauf, Nasser M Aldekhail, Filip Van Nieuwerburgh, Sami Siraj , journal (2026) — Prof. Dr. Sami Siraj
• Investigating the Role of Vitamin D in Enhancing Duloxetine and Fluoxetine Efficacy: Mechanistic Insights Into NRF2 Activation, Oxidative Stress, and Neurochemical Modulation — Naveed Khan, Shakir Ullah, Muhammad Ilyas, Muhammad Waseem Khan , Journal (2025) — Dr. Shakir Ullah
• Evaluation of the laxative effects of Taraxacum officinale using experimental animal models. — Ali HZ, Ali N, Nabi M, Ali M, Jahan S , journal (2025) — Prof. Dr. Niaz Ali
• The molecular mechanisms of liver and islets of Langerhans toxicity by benzene and its metabolite hydroquinone in vivo and in vitro (vol 25, pg 628, 2015) — Haji Bahadar, Faheem Maqbool, Sara Mostafalou, Maryam Baeeri, Mahdi Gholami, Elmira Ghafour-Boroujerdi, Mohammad Abdollahi , Journal (2025) — Dr. Haji Bahadar
• Association of Human Leukocyte Antigen (HLA) Class II Alleles of DQB1 (DQB1*03:02) (DQB1*06:02) and DRB1 (DRB1*04:01) with Type-1 Diabetes Patients of Khyber Pakhtunkhwa, Pakistan — Aiman Begaum Qudsia Hina, Zakiullah, Haji Bahadar, Haseenullah Shah, Mohammad Sajjad Afridi, Sobia Kulsoom Awan, Maqsood Ali, Kiran Ijaz, Hira Siyar , Journal (2024) — Ms. Hira Siyar
• Impact of gender on long-term clinical outcomes and major adverse cardiovascular events in patients undergoing percutaneous coronary intervention receiving clopidogrel therapy: A follow-up study — Waheed Iqbal, Abdur Razaq, Syed Tahir Shah, Shafiq Ahmad Tariq, Sheema Rahim, Sami Siraj , journal (2026) — Prof. Dr. Sami Siraj
• Linezolid versus Azithromycin for Follicular Tonsillitis in Children Aged 2 to 6: A Comparative Evaluation — Dr Momina Naz Dr Zainab Irshad Khan , Dr Nasir Ahmad, Dr Mohammad Arif , Dr Falak Naz, Dr Muhammad Hassan Ali Khan , Journal (2024) — Dr. Nasir Ahmad
• Naveed Khan, Shakir Ullah, Muhammad Ilyas, Muhammad Waseem Khan — Sardar Ali, Saima Nawaz, Shakir Ullah, Zainab Irshad, Niaz Ali, Ahad Nawaz, Muhammad Riaz, Najm Ur Rahman , Journal (2025) — Dr. Shakir Ullah
• Corrigendum to “α-Lipoic acid prevents senescence, cell cycle arrest, and inflammatory cues in fibroblasts by inhibiting oxidative stress”[Pharmacol. Res. 141 (2019) 214–223] — Maryam Baeeri, Haji Bahadar, Mahban Rahimifard, Mona Navaei-Nigjeh, Reza Khorasani, Mohammad Amin Rezvanfar, Mahdi Gholami, Mohammad Abdollahi , Journal (2024) — Dr. Haji Bahadar
• New Lead Schiff Bases Predominantly Mediate Vasorelaxant Activity Throughα1 Receptor Blocking Activity — Subhan,Z.; Ali,N.; Ullah, A.; Ali, W.; Nabi, M.;Shah,S.W.A , Journal (2025) — Prof. Dr. Niaz Ali
• A Comparison of the Protective Effect of Pyridoxine and N-Acetylcysteine in Paracetamol Induced Hepatotoxicity in Rats — Ghazala Bibi, Arooj Javed , Hira Siyar, haji bahadar , Journal (2024) — Ms. Hira Siyar
• Renoprotective Effect of Captopril on Tacrolimus-Induced Renotoxicity in Mice” — Irshad, Sidra, Abdul Hameed Khan, Niaz Ali, Bushra Nasib, Muhammad Nabi, Najma Salahuddin, Rizwan Faisal, and Shakir Ullah. , Journal (2025) — Prof. Dr. Niaz Ali
• Modulation of oxidative stress/NMDA/nitric oxide pathway by topiramate attenuates morphine dependence in mice — Shabir Hussain, Haji Bahadar, Muhammad Imran Khan, Neelum Gul Qazi, Shabnum Gul Wazir, Habab Ali Ahmad , Journal (2024) — Dr. Haji Bahadar
• SARS-CoV-2 variants and genomic surveillance in the low-resource north-west region of Pakistan — Steve Harakeh &Yasar Mehmood Yousafzai Muhammad Waseem Shah,Muhammad Iqbal Qureshi,Ishaq Nasib Khan,Muhammad Zakria,Shahzad Ahmad,Tariq Rahim,Nasir Ahmad,Hafsah Muhammad,Sami Siraj,Asif Ali,Saeed Ahmed , journal (2024) — Dr. Nasir Ahmad
• Spectrum of Haemoglobinopathies in Tertiary Care Hospital of Rawalpindi and Islamabad. — Tanveer Ul Haq Zia, Ammar Ahmed, Muhammad Ilyas, Hira Siyar, Haji Bahadar , Journal (2024) — Ms. Hira Siyar
• Antidepressant effects of SY-2476: A caffeine derivative’s role in A1/A2A gene expression modulation in corticosterone-induced depressed rats — Irfan Khan, Saif Ullah, Shakir Ullah, Niaz Ali, Zilli Huma, Sedat Yaşar, Siraj Khan, Rizwan Ul Haq, Amjad Khan, Imran Khan , Journal (2025) — Dr. Shakir Ullah
• Ambroxol’s Role in PTZ-Induced Anxiety-Like Conditions in Mice: Targeting Neuroinflammation and Oxidative Stress via In Vivo and In Silico Approaches — Hafeeza Zafar Ali, Sarwat Jahan, Laila Ilahi, Sami Siraj, Muhammad Zakria, Najeeb Ullah, Muhammad Ikram, Ashraf Ullah Khan, Manzoor Khan, Fawad Ali Shah & Hafsah Muhammad , journal (2025) — Prof. Dr. Sami Siraj
• Association of GABRG2 rs211037 Gene Polymorphism With Epilepsies and Pharmacoresistance to Anti-Epileptic Drugs; A Meta-Analysis — Muhammad Ikram Shakir Ullah, Saad Ali, Nasir Ahmad, Muhammad Zakria, Muhammad Nabi , Journal (2023) — Dr. Nasir Ahmad
• Evaluation of Anticoagulant Effect of Alum in Rats. — Muhammad Hassan Ali Khan, Ghazala Bibi, Hira Siyar, Haji Bahadar , Journal (2024) — Ms. Hira Siyar
• Bleeding Events Associated with Rivaroxaban Therapy in Naive Patients with Nonvalvular Atrial Fibrillation: A Longitudinal Study from a Genetic Perspective with INR Follow-Up — 2 and Shujaat Ahmad Nur Ul Ain 1,2, Niaz Ali 3,* , Abid Ullah 4 , Shakir Ullah 1 , Journal (2024) — Dr. Shakir Ullah
• Muscle relaxant and antipyretic effects of pentacyclic triterpenes isolated from the roots of Diospyros lotus L — Ajmal Khan, Hamdy Kashtoh, Abdur Rauf, Sobia Ahsan Halim, Awan A Aleem, Haji Bahadar, Huma Shareef, Fazal Mabood, Asaad Khalid, Kwang-Hyun Baek, Ahmed Al-Harrasi , Journal (2024) — Dr. Haji Bahadar
• Antihypertensive Activity of Flowering Twigs of Calotropis Procera (Ait.) Is Predominantly Mediated through Vasorelaxant Pathway — Ullah, Wahib, Niaz Ali, Abid Ullah, and Muhammad Nabi , Journal (2025) — Prof. Dr. Niaz Ali
• Impact of CYP2C19*2 on Clopidogrel Response and Cardiovascular Outcomes in ST-segment elevation myocardial infarction Patients — Abdur Razaq 1, Waheed lqbal 2, Syed Tahir Shah 3, Mohsin Ali 4, Sami Siraj 5, , journal (2026) — Prof. Dr. Sami Siraj
• The anticonvulsant and antioxidant effect of Rosa moschata (J) fruit extract in pentylenetetrazole induced epileptic mouse model — Imran Khan1 and Muhammad Nabi Zainab Irshad1, Samia Nawaz1, Shakir Ullah1*#, Niaz Ali1 , Journal (2024) — Dr. Shakir Ullah
• Antidepressant effects of SY-2476: A caffeine derivative’s role in A1/A2A gene expression modulation in corticosterone-induced depressed rats — Irfan Khan, Saif Ullah, Shakir Ullah, Niaz Ali, Zilli Huma, Sedat Yaşar, Siraj Khan, Rizwan Ul Haq, Amjad Khan, Imran Khan , Journal (2025) — Prof. Dr. Niaz Ali
• The lipid-lowering efficacy of rosuvastatin is associated with variations in SLCO1B1: a 12-month prospective cohort study — S. SIRAJ M. ZAKRIA, A. HUSSAIN, N. AHMAD, N. AHMED, M.A. RAUF , Journal (2023) — Dr. Nasir Ahmad
• Association of CYP2C19 gene single nucleotide polymorphisms (rs12248560 and rs4244285) with response to thalidomide in transfusion dependent β-thalassemia patients- a 12-months follow-up study — Inayat Ur Rahman, Muhammad Shahid, Muhammad Tariq Humayun Khan, Naseer Ahmed, Shafiq Ahmad, Amir Muhammad, Sher Afghan Khan, Abdus Saboor, Muhammad Tariq Masood Khan, Sami Siraj , journal (2025) — Prof. Dr. Sami Siraj
• Association of ABCC2 gene polymorphism (rs3740066) with thalidomide-induced peripheral neuropathy in transfusion-dependent β-thalassemia patients: a case–control study from … — Shafiq Ahmad, Sami Siraj, Inayat Ur Rahman, Muhammad Shahid, Ghazala Shaheen, Umar Aleem , journal (2025) — Prof. Dr. Sami Siraj

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